Anterograde Amnesia and Temporally Graded Retrograde Amnesia for a Nonspatial Memory Task after Lesions of Hippocampus and Subiculum
نویسندگان
چکیده
منابع مشابه
Anterograde amnesia and temporally graded retrograde amnesia for a nonspatial memory task after lesions of hippocampus and subiculum.
We studied the importance of the hippocampus and subiculum for anterograde and retrograde memory in the rat using social transmission of food preference, a nonspatial memory task. Experiment 1 asked how long an acquired food preference could be remembered. In experiment 2, we determined the anterograde amnesic effects of large lesions of the hippocampus that included the subiculum. In experimen...
متن کاملCholinergic deafferentation of the hippocampus causes non-temporally graded retrograde amnesia in an odor discrimination task.
Dementia of the Alzheimer's type (DAT) is a neurodegenerative disorder marked by loss of hippocampal cholinergic tone and significant memory impairments, specifically for memories acquired prior to disease onset. The nature of this relationship, however, remains debated. The current study used the string pulling task to evaluate the temporal effects of odor discrimination learning in animals wi...
متن کاملKetamine induces anterograde and retrograde amnesia in rats
Introduction: The N-methyl-D-aspartate (NMDA) receptors, which have been implicated in memory formation, could be noncompetitively blocked by ketamine. The present study examines the short term effect of ketamine on induction of anterograde and retrograde amnesia in male rats using Morris water maze (MWM). Methods: Male N-MRI rats were randomly divided into nine experimental groups. MWM stud...
متن کاملAnterograde and retrograde amnesia in rats with large hippocampal lesions.
A test of socially acquired food preferences was used to study the effects of large lesions to the hippocampal formation (HPC) on anterograde and retrograde memory in rats. In the anterograde test, rats with HPC lesions normally acquired the food preference but showed a faster rate of forgetting than control groups. When the food preference was acquired preoperatively, HPC groups exhibited a te...
متن کاملProlonged inactivation of the hippocampus reveals temporally graded retrograde amnesia for unreinforced spatial learning in rats.
We investigated whether systems consolidation of spatial memory could be detected in a non-navigational, spatial-learning test that takes advantage of rats' natural propensity to preferentially investigate an object that was displaced relative to spatial cues more than an object that remained stationary. Previous studies using navigational spatial-learning tests have generally failed to reveal ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2002
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.22-11-04663.2002